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Selected Projects

Gx Capture Pro 1.0
pQCT images measurements
Cell images segmentation
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Live measurement in industry or life science to may reach 0.5 microns
CIS currently collaborates with its business partner GT Vision on GX Capture Pro 1.0 development. The application package consists of a core module and two additional application modules. The functions of core module are camera and hardware control - such as auto/manual exposure, auto white balance, and shading correction etc. - and Image achieve, calibration setup, interactive measurements, timelapse image sequence acquisition, movie record etc. GX Capture Pro 1.0 is ideally suited to support simple microscope or advanced users.
3DImg
Image extension module:

The image extension module is developed for the field extension of thin specimen or for focus extension of thick specimens. Advanced algorithms have been used for 2D images or for measuring the focus in a 3D stack. From the individual focus score, the module reconstructs a 3D tessellation to present the specimen in 3D. Different texture and pseudo colour schema options can be used and apply to the tessellation results. The final result is exported in 2D and 3D format allowing samples to be printed on the 2D or 3D printer.

Template measurement module:

Template measurement is an advanced measurement module. This module helps clients to identify quickly and accurately any fault in their biological specimen sample, or industrial part. A standard template overlay can be defined and applied to the system. The operators only need to scan or resize the overlay by dragging the template. By comparison of the reference template and current sample/specimen, the operator can classify the measurement result quickly.

pQCT images reconstruction and bone shape retrieval and measurement

This project collaborated with MRC Nutrition Research Cambridge. The goal of this research was to find the tibia and fibula bone boundary. From the bone boundaries, further measurement of cortical thickness and cortical thickness in the direction of Imax and Imin were measured and the bone symmetry estimated. Approximately 22 standard or self-defined measurement parameters were identified. The total measurements were modelled and analysed. Final measurement results were reported and classified based on different statistical models.
Enhanced Characterization of Cortical Bone Using Novel pQCT Shape Software, Journal of Clinical Densitometry: Assessment of Skeletal Health, pp.247-255, vol 13, 2010

Cell recognition and channels colocalisation

This project collaborated with MRC National Institute for Medical Research. The purpose of this research was to identify cells stained with different fluorescent dyes. The cells were identified and counted by our intelligent algorithms. The cells in the different colour channels were compared and colocalised. The distribution patterns of the differently stained cells were estimated and then analysed.
Applying an Adaptive Watershed to the Tissue Cell Quantification During T-Cell Migration and Embryonic Development, Chapter 14, T-Cell Trafficking Methods and Protocols, Springer Press, September 2010